p38/JNK Is Required for the Proliferation and Phenotype Changes of Vascular Smooth Muscle Cells Induced by L3MBTL4 in Essential Hypertension

Figure 2

p38/JNK was required for vascular remodeling mediated by L3MBTL4. (a) Representative photomicrographs of hematoxylin-eosin staining in blood vessels from WTs, TG + normal saline, TG + SP600125, and TG + SB2003580 (n = 5 each group). (b)–(f) The media thickness, vessel diameter, media area, lumen area, and media/lumen area ratio of aortas in each group was quantified (n = 5 per group). The magnification was 2.5-fold and 20-fold. Scale bars are 50 μm and 10 μm. ; ; . All data represent mean ± SEM.

(a)

(b)

(c)

(d)

(e)

(f)