p38/JNK Is Required for the Proliferation and Phenotype Changes of Vascular Smooth Muscle Cells Induced by L3MBTL4 in Essential Hypertension

Figure 4

p38/JNK was required for propelled cell cycle mediated by L3MBTL4. (a) The percentage of cells in G0/G1, S, and G2/M phases of cell cycle in NC, L3MBTL4 overexpression VSMCs, L3MBTL4 overexpression VSMCs + SP600125, and L3MBTL4 overexpression VSMCs + SB2003580 was quantified by flow cytometer analysis (n = 3). (b) Western blot analysis of cyclin A, cyclin D, p21, and p27 expression (n = 3). ; ; .

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