Mortality in Elderly Patients Taking Furosemide: Prospective Cohorts Study
Table 1
Basal characteristics and causes of death of the sample included in the analysis.
Total (686)
Alive (n = 460)
Deceased (n = 226)
No furosemide (n = 630)
Furosemide (n = 56)
Women
434,00
302 (65.7%)
132 (58.41%)
0.773
397 (63.0%)
37 (66.1%)
0.773
No tobacco
488,00
335 (73.1%)
153 (67.7%)
0.445
449 (71.5%)
39 (69.6%)
0.445
No alcohol
455,00
293 (63.7%)
162 (72.3%)
0.303
414 (65.9%)
41 (73.2%)
0.303
High BP
353,00
236 (51.3%)
117 (51.77%)
0.405
321 (51.0%)
32 (57.1%)
0.405
No heart disease
503,00
350 (76.1%)
153 (67.7%)
<0.001
482 (76.5%)
21 (37.5%)
<0.001
Age
81.39 (7.1)
79.5 (6.9)
85.3 (5.7)
<0.001
81.2 (7.1)
83.9 (6.5)
0.002
Body mass index
28.7 (4.8) 28.2 (IQR = 5.7)
28.8 (4.8) 28.3 (IQR = 5.5)
28.4 (4.9) 27.9 (IQR = 6.5)
0.350
28.6 (4.7) 28.2 (IQR = 5.6)
29.5 (6.2) 27.9 (IQR = 6.5)
0.641
Katz index
1.1 (1.8) 0 (IQR = 1)
0,6 (1.3) 0 (IQR=1)
2.0 (2.3) 1 (IQR=4)
<0.001
1.0 (1.8) 0 (IQR=1)
1.9 (2.3) 0.5 (IQR=4)
0.007
Muscle strength
28.8 (8.4) 33 (IQR = 7)
30.4 (6.6) 34 (IQR=4)
25.2 (10.6) 30 (IQR=15)
<0.001
29.1 (8.1) 33 (IQR=6)
24.6 (10.7) 29 (IQR=18)
0.004
Comorbidity
3.4 (2.1) 3 (IQR = 3)
3.3 (2.0) 3 (IQR = 3)
3.4 (2.3) 3 (IQR = 3)
0.697
3.3 (2.0) 3 (IQR=3)
4.4 (2.5) 4 (IQR=5)
<0.001
Pfeiffer index
1.7 (2.1) 1 (IQR = 2)
1.2 (1.6) 1 (IQR=2)
2.6 (2.8) 1.5 (IQR=4)
<0.001
1.6 (2.1) 1 (IQR=2)
2.6 (2.8) 1 (IQR=4)
0.013
Systolic BP
141.3 (22.8) 140 (IQR = 28)
141.9 (22.2) 140 (IQR = 28.8)
140.2 (24.0) 140 (IQR = 27.3)
0.365
141.8 (22.6) 140 (IQR=27)
136.1 (25.0) 134 (IQR=27.0)
0.007
Diastolic BP
79.8 (13.4) 80 (IQR = 18)
81.0 (12.77) 81 (IQR=17)
77.3 (14.2) 77 (IQR=19)
<0.001
80.2 (13.4) 80 (IQR=17)
75.6 (12.7) 75.5 (IQR=19.3)
0.015
PP
61.5 (18.9) 59 (IQR = 24.8)
60.8 (18.3) 59 (IQR = 23)
62.8 (20.1) 59.0 (IQR = 29.3)
0.346
61.6 (18.7) 59 (IQR = 25)
60.4 (21.2) 56.5 (IQR = 23.8)
0.401
O2 saturation
94.8 (3.8) 96(IQR = 3)
95.2 (3.3) 96 (IQR=3)
94.0 (4.5) 95 (IQR=4)
0.002
94.9 (3.76) 96 (IQR = 3)
93.9 (3.9) 95 (IQR = 5)
0.076
Data presented are n (%) or mean (SD) or median (interquartile range–IQR). BP: blood pressure; PP: pulse pressure; comorbidity: number of diseases. Numbers in bold mean statistical significance.
