Clinical Study

Activation of T Lymphocytes in Response to Persistent Bacterial Infection: Induction of CD11b and of Toll-Like Receptors on T Cells

Figure 1

Expression of CD11b and CD28 on CD4+ T cells of patients with implant-associated osteomyelitis and of healthy donors: (a) by cytofluorometry expression of CD11b and CD28 were determined. The gate was set for CD4+ cells. With regard to CD11b and CD28 expressions, four populations were detected: CD28+CD11b-, CD28+CD11b+, CD28-CD11b-, and CD28-CD11b+ (an example for a patient and a donor is shown in (a) (The numbers give the percentage of CD4+ found in the respective quadrant.) (b) The percentage of CD4+CD11b+ in the patients and the donors is shown. The horizontal bar indicates the median value. The mean values for the patients (mean ± SD 5.6 ± 5.3%) differed significantly from that obtained for the donors (2.2 ± 2.4%) as calculated by ANOVA
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(a)
526740.fig.001b
(b)