Research Article

Gene Profiling of Aortic Valve Interstitial Cells under Elevated Pressure Conditions: Modulation of Inflammatory Gene Networks

Table 3

Down regulated genes related to inflammation. All genes had a .

Ensembl gene IDGene nameDescriptionFold change

ENSSSCG00000005055LGALS3Lectin, galactoside-binding, soluble, 3−1.575
ENSSSCG00000011993PROS1Protein S (alpha)−1.654
ENSSSCG00000011399GNAI2Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2−1.69
ENSSSCG00000001408AIF1Allograft inflammatory factor 1 (AIF-1)(Ionized calcium-binding adapter molecule 1)(Protein G1)−1.715
ENSSSCG00000014310CXCL14Chemokine (C-X-C motif) ligand 14−1.73
ENSSSCG00000013030PRDX5Peroxiredoxin 5−1.751
ENSSSCG00000014219CDO1Cysteine dioxygenase, type I−1.791
ENSSSCG00000012840CD151CD151 molecule (Raph blood group)−1.851
ENSSSCG00000015997PRKRAProtein kinase, interferon-inducible double stranded RNA dependent activator pseudogene 1−1.927
ENSSSCG00000006612S100A10S100 calcium binding protein A10−1.937
ENSSSCG00000007982MPGN-methylpurine-DNA glycosylase−1.949
ENSSSCG00000015570IVNS1ABPInfluenza virus NS1A binding protein−1.963
ENSSSCG00000014170CASTCalpastatin−2.067
ENSSSCG00000006661VPS45Vacuolar protein sorting 45 homolog (S. cerevisiae)−2.105
ENSSSCG00000000125LGALS1Lectin, galactoside-binding, soluble, 1−2.133
ENSSSCG00000009565GAS6Growth arrest-specific 6−2.193
ENSSSCG00000008428MSH2MutS homolog 2−2.509
ENSSSCG00000013252F2Prothrombin Precursor (EC 3.4.21.5) (Coagulation factor II)−2.746
ENSSSCG00000005512C5Complement component 5−2.793
ENSSSCG00000017473TOP2ATopoisomerase (DNA) II alpha 170 kDa−4.029
ENSSSCG00000009330ALOX5APArachidonate 5-lipoxygenase-activating protein−4.058