Definition of Nonresponse to Analgesic Treatment of Arthritic Pain: An Analytical Literature Review of the Smallest Detectable Difference, the Minimal Detectable Change, and the Minimal Clinically Important Difference on the Pain Visual Analog Scale

Figure 2

Minimal clinically important difference by tertile of baseline VAS score. The light, medium, and dark gray sections of the VAS (30–49, 50–65, and >65) correspond to the rounded tertiles of baseline pain VAS scores reported by Tubach et al. [30]. Arrows depict the MCID for improvement reported by Tubach et al. (osteoarthritis of knee and hip) [30] and Hägg et al. (back pain) [18].