Research Article

Atherosclerotic Plaque Stability Is Affected by the Chemokine CXCL10 in Both Mice and Humans

Figure 3

Plaque concentrations of CXCL10 are associated with lesion morphology. Individual values were divided over quartiles (see Figure 1). By using ANOVA, we tested to see if plaque CXCL10 concentrations associated with lesion morphology. Increasing plaque concentrations of CXCL10 were indeed associated with an increase in atheromatous-type lesions (a) and a decrease of SMC dominant lesions and an increase of macrophage dominant lesions (b).
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(a)
936109.fig.003b
(b)