Chemokine Expression in Human Astrocytes in Response to Shiga Toxin 2

Figure 4

Chemokine release by HASTs upon stimulation with Stx2. Secretion of IL-8 (a) and MCP-1 (b) by HASTs treated with 10⁻⁹ or 10⁻¹⁰ mol/L Stx2 for 24 or 48 h. IL-8 and MCP-1 were measured in cell culture supernatants using ELISA. Data are the means ± SD from the five experiments. Levels of Stx2-induced IL-8 or MCP-1 and those in the untreated controls were calculated. ^∗𝑃<0.05 and ^∗∗𝑃<0.01.

(a)

(b)