Clinical Study

Intravitreal Dexamethasone in the Management of Delayed-Onset Bleb-Associated Endophthalmitis

Table 1

Baseline demographics, clinical presentation, and initial culture results.

IVDNo IVD value
70/83 (84%)13/83 (16%)

Age
 Mean, SD74 yr (12)70 yr (14)0.27
Gender
 Female34 (49%)8 (62%)0.39
 Male36 (51%)5 (39%)
Diabetes mellitus
 Present9 (13%)2 (15%)0.81
 Absent61 (87%)11 (85%)
Antimetabolites (MMC or 5FU)
 Used45 (64%)7 (54%)0.47
 Not used25 (36%)6 (46%)
Mean time of onset, SD60 mo (43)49 mo (55)0.46
Bleb leak
 Present16 (23%)5 (38%)0.23
 Absent54 (77%)8 (62%)
Anterior chamber
 Hypopyon48 (69%)10 (77%)0.55
View to fundus
 Hazy22 (31%)8 (62%)0.04
 Poor/none48 (69%)5 (39%)
Intraocular Pressure
 Presentation, SD20 (14)19 (12)0.8
Treatment, initial
 Tap and injection41 (59%)12 (92%)0.03
 Pars plana vitrectomy29 (41%)1 (8%)
Treatment, additional
 Filtering procedure12 (17%)1 (8%)0.39
 Pars plana vitrectomy21 (30%)2 (15%)0.28
Culture results
 Culture positive46 (66%)6 (46%)0.18
 Culture negative24 (34%)7 (54%)
Gram-positive cases33 (47%)4 (31%)0.28
Streptococcus 19 (27%)2 (15%)0.37
 Coagulase-negative Staphylococcus 7 (10%)2 (15%)0.57
Enterococcus 6 (9%)00.27
Staphylococcus aureus 1 (1%)00.67
Gram-negative cases12 (17%)2 (15%)0.88
Moraxella 8 (11%)00.2
Pseudomonas 2 (3%)1 (8%)0.39
Serratia 1 (1%)1 (8%)0.18