Clinical Study
Intravitreal Dexamethasone in the Management of Delayed-Onset Bleb-Associated Endophthalmitis
Table 1
Baseline demographics, clinical presentation, and initial culture results.
| | IVD | No IVD | value | | 70/83 (84%) | 13/83 (16%) |
| Age | | | | Mean, SD | 74 yr (12) | 70 yr (14) | 0.27 | Gender | | | | Female | 34 (49%) | 8 (62%) | 0.39 | Male | 36 (51%) | 5 (39%) | | Diabetes mellitus | | | | Present | 9 (13%) | 2 (15%) | 0.81 | Absent | 61 (87%) | 11 (85%) | | Antimetabolites (MMC or 5FU) | | | | Used | 45 (64%) | 7 (54%) | 0.47 | Not used | 25 (36%) | 6 (46%) | | Mean time of onset, SD | 60 mo (43) | 49 mo (55) | 0.46 | Bleb leak | | | | Present | 16 (23%) | 5 (38%) | 0.23 | Absent | 54 (77%) | 8 (62%) | | Anterior chamber | | | | Hypopyon | 48 (69%) | 10 (77%) | 0.55 | View to fundus | | | | Hazy | 22 (31%) | 8 (62%) | 0.04 | Poor/none | 48 (69%) | 5 (39%) | | Intraocular Pressure | | | | Presentation, SD | 20 (14) | 19 (12) | 0.8 | Treatment, initial | | | | Tap and injection | 41 (59%) | 12 (92%) | 0.03 | Pars plana vitrectomy | 29 (41%) | 1 (8%) | | Treatment, additional | | | | Filtering procedure | 12 (17%) | 1 (8%) | 0.39 | Pars plana vitrectomy | 21 (30%) | 2 (15%) | 0.28 | Culture results | | | | Culture positive | 46 (66%) | 6 (46%) | 0.18 | Culture negative | 24 (34%) | 7 (54%) | | Gram-positive cases | 33 (47%) | 4 (31%) | 0.28 | Streptococcus | 19 (27%) | 2 (15%) | 0.37 | Coagulase-negative Staphylococcus | 7 (10%) | 2 (15%) | 0.57 | Enterococcus | 6 (9%) | 0 | 0.27 | Staphylococcus aureus | 1 (1%) | 0 | 0.67 | Gram-negative cases | 12 (17%) | 2 (15%) | 0.88 | Moraxella | 8 (11%) | 0 | 0.2 | Pseudomonas | 2 (3%) | 1 (8%) | 0.39 | Serratia | 1 (1%) | 1 (8%) | 0.18 |
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