Intravitreal Dexamethasone in the Management of Delayed-Onset Bleb-Associated Endophthalmitis

Table 5

Comparative studies of IVD for bacterial endophthalmitis.

	Clinical setting		Culture results		Inflammation	VA outcomes	Time
	n	Staph epi.	Strep/Enterococcus	Gram-negative
Das et al. [5]	Postcataract and trauma
IVD	29	n/a	n/a	n/a	2.6 score	86% success	3 months
No IVD	34				3.2 score^1	71% success
Shah et al. [8]	Postcataract
IVD	26	31%	12%	0	n/a	20/70 median	6 months
No IVD	31	35%	13%	3%		20/50 median^2
Gan et al. [6]	Postcataract
IVD	16	39%	8%	0	n/a	85% 20/200 or better	3 months
No IVD	13	50%	6%	0		50% 20/200 or better^3
Hall et al. [7]	Postcataract
IVD	26	46%	23%	0	0.3 cell/flare	20/40 median	last followup
No IVD	38	37%	5%	0	0.3 cell/flare	20/50 median
Jacobs et al.	Bleb-associated
IVD	70	10%	36%	17%	n/a	7/200 mean	3 months
No IVD	13	15%	15%	15%		3/200 mean^4

¹Relative change in inflammation showed statistical significance at 1 and 4 weeks, not at 3 months. ²𝑃<0.05,³𝑃=0.055. ⁴Relative logMARΔ showed statistical significance at 1 month, not at 3 months.