Cytosolic Double-Stranded DNA as a Damage-Associated Molecular Pattern Induces the Inflammatory Response in Rat Pancreatic Stellate Cells: A Plausible Mechanism for Tissue Injury-Associated Pancreatitis
Figure 6
Model for mechanisms triggered by intracellular double-stranded DNA (dsDNA) in PSCs. The scheme depicts the induction of the innate immune response by dsDNA reflecting the onset and exacerbation of pancreatitis under sterile an nonsterile conditions.