Reactive Oxygen Species, SUMOylation, and Endothelial Inflammation

<table>SUMOylation process. Protein SUMOylation consists of deconjugation and conjugation pathways. SUMO-conjugation requires three classes of enzymes (E1<svg height="7.125" id="M1" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 19.8125 7.125" width="19.8125" xmlns="http://www.w3.org/2000/svg">
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</svg> E2 <svg height="7.125" id="M2" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 19.8125 7.125" width="19.8125" xmlns="http://www.w3.org/2000/svg">
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</svg> E3). SUMO-deconjugation requires the sentrin/SUMO-specific proteases (SENP2).   </table>

International Journal of Inflammation

Reactive Oxygen Species, SUMOylation, and Endothelial Inflammation

Figure 1