Review Article

Blocking Neurogenic Inflammation for the Treatment of Acute Disorders of the Central Nervous System

Figure 2

Neurogenic inflammatory initiation of vasogenic edema. PLC—phospholipase C, IP3—inositol triphosphate, —intracellular calcium ions, CGRP—calcitonin gene-related peptide, SP—substance P, CRLR—calcitonin receptor-like receptor, RAMP—receptor activity modifying protein, NK1—NK1 receptor, EC—endothelial cell.
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