Evolution of the Macrophage CD163 Phenotype and Cytokine Profiles in a Human Model of Resolving Inflammation
Figure 1
Leukocyte infiltration into cantharidin-induced skin blisters. Quadruplicate skin blisters were established by topical application of cantharidin (0.1%) to the forearm of 10 healthy individuals. Blister fluid was collected from duplicate blisters at 16 h and 40 h, respectively, and analyzed as follows (a) Fluid volume (mL) and cellularity (105). Each point represent the average from 2 skin blisters; horizontal lines represents the population mean. (b) Differential leukocyte subpopulations. PMN: polymorphonuclear phagocytes; EOS: eosinophils; LYMPH: lymphocytes; MONO: monocytes/macrophages.
