Evolution of the Macrophage CD163 Phenotype and Cytokine Profiles in a Human Model of Resolving Inflammation

<table>Enzyme-linked immunosorbent assay (ELISA) detection of inflammatory regulators in blister fluid: (a) MCP-1/CCL2, (b) IL-8/CXCL8, (c) MDC/CCL22, and (d) TGF<i>β</i>. Blister fluid from <svg height="11.125" id="M22" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 44.400002 11.125" width="44.400002" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> individuals was analyzed by ELISA in duplicate, at each of the timepoints. Results are expressed as mean <svg height="9.5625" id="M23" style="vertical-align:-0.3003pt" version="1.1" viewbox="0 0 10.1 9.5625" width="10.1" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> values represent statistical differences between 16-hour and 40-hour timepoints analyzed by unpaired <i>t</i> test.</table>

International Journal of Inflammation

fig4

Figure 4

Figure 4: Evolution of the Macrophage CD163 Phenotype and Cytokine Profiles in a Human Model of Resolving Inflammation 