CCR7 Receptor Expression in Mono-MAC-1 Cells: Modulation by Liver X Receptor α Activation and Prostaglandin E₂

Table 2

Statistical analyses of CCR7 surface expression in MM-1 cells.

	Mean % of positive cells	SD	value	Mean MFI	SD	value
24 h
Untreated	16,04	2,21		4,32	0,54
PGE2	36,40	5,67	0.0044	9,24	1,55	0.0066
T0901317	11,32	1,86	0.047	4,76	0,72	0.45
PGE2 + T0901317	26,83	2,06	0.0038	6,68	1,18	0.035
48 h
Untreated	6,11	2,04		3,32	0,76
PGE2	17,81	3,99	0.011	7,59	2,13	0.030
T0901317	5,07	2,49	0.61	3,71	0,88	0.57
PGE2 + T0901317	20,11	2,48	0.0016	8,06	1,69	0.011

Data represent mean ± standard deviation (SD) of three independent flow cytometry experiments after 24 or 48 h of treatment with 1 μM PGE₂ and/or 1 μM T0901317.