Research Article
Nicotine Inhibits Clostridium difficile Toxin A-Induced Colitis but Not Ileitis in Rats
Figure 3
The anti-inflammatory effect of nicotine on the rat colon is mediated by nicotinic receptors because the specific nicotinic receptor antagonist, hexamethonium, significantly inhibited the protective effects of nicotine on toxin A-induced luminal fluid accumulation (a) and MPO content (b) in the colon. versus control; versus control; versus toxin A; versus toxin A + nicotine; .
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