Hyperexcitability in Spinal WDR Neurons following Experimental Disc Herniation Is Associated with Upregulation of Fractalkine and Its Receptor in Nucleus Pulposus and the Dorsal Root Ganglion

<div>(a) Examples of qPCR amplification plots demonstrating the presence IL-1<i>β</i> (red), TNF (green), Csf1 (blue), CX3CL1 (brown), and CX3CR1 (yellow) in native NP tissue. (b) Examples of single cell recordings at baseline, 12 minutes and 90 minutes after nucleus pulposus conditioning alone. (c) Examples of single cell recordings at baseline, 12 minutes and 90 minutes after nucleus pulposus conditioning together with minocycline.</div>

International Journal of Inflammation

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Figure 1: Hyperexcitability in Spinal WDR Neurons following Experimental Disc Herniation Is Associated with Upregulation of Fractalkine and Its Receptor in Nucleus Pulposus and the Dorsal Root Ganglion 

Figure 1 | Hyperexcitability in Spinal WDR Neurons following Experimental Disc Herniation Is Associated with Upregulation of Fractalkine and Its Receptor in Nucleus Pulposus and the Dorsal Root Ganglion 