Insights into DNA Platination within Unusual Structural Settings

Figure 10

Methyl proton resonance region of the 600 MHz 1D ¹H NMR spectra of the reaction between [Pt(¹⁵NH₃)₂I₂], I, and phosphorothioate octamer ODN d(CGCGsTGCG), VIIs. (a) After 1 hr; (b) 5 hrs; (c) 9 hrs; (d) 13 hrs; (e) 17 hrs; (f) 21 hrs; (g) 68 hrs. Boxed signals: intermediates; downward arrows: starting materials; upward arrows: end products.