Mixed-Ligand Nickel(II) Complexes Containing Sulfathiazole and Cephalosporin Antibiotics: Synthesis, Characterization, and Antibacterial Activity

Table 2

IR spectral data of the drugs and the complexes (cm⁻¹).

	𝜈C=O	𝜈C=O	𝜈COO	𝜈COO	Δ𝜈	𝜈C=N	𝜈Ni–N
Compound	Lactam	Amide	Asymm.	Symm
Cefazolin	1765	1650	1600	1380	220
[Ni(L1)(stz)(H2O)]	1749	1650	1580	1370	210		425
Cephalothin	1730	1650	1620	1400	220
[Ni(L2)(stz)]	1715	1650	1610	1390	220		430
Cefotaxime	1780	1640	1600	1375	225	1610
[Ni(L3)(stz)]	1750	1640	1590	1370	220	1605	426
Ceftriaxone	1774	1667	1610	1400	210	1610
[Ni(L4)(stz)(H2O)]	1755	1661	1600	1385	215	1610	430
Cefepime	1770	1650	1600	1390	210	1600
[Ni(L5)(stz)]Cl	1740	1650	1590	1380	210	1590	415