Research Article

Synthesis, Characterization, and Biological Evaluation of Some 3d-Metal Complexes of Schiff Base Derived from Xipamide Drug

Table 5

Diuretic screening data of the pure drug, ligand, and its metal complexes.

GroupLigand/complexesAverage volume of urine (μL) Final average (μL)
1:00 PM3:00 PM5:00 PM

IControl113.94167.22118.01
IIXipamide155.66208.09266.91
IIIL175.75235.48289.10
IVHgL2265.54283.12343.12
VVOL2386.66375.29378.57