Pharmacophore Modelling and Synthesis of Quinoline-3-Carbohydrazide as Antioxidants

Table 1

Summary of hypothesis.

Hypo	Feature	Rank	Direct hit mask	Partial hit mask
1	RAAA	36.68	01111	10000
2	RAAA	36.43	01111	10000
3	RAAA	36.29	01111	10000
4	AAAA	36.04	11101	00010
5	AAAA	35.82	11101	00010
6	RAAA	35.67	11111	10000
7	AAAA	35.19	11101	00010
8	HAAA	34.10	01111	10000
9	HAAA	33.70	01111	10000
10	HAAA	33.52	01111	10000

In direct hit mask, (1) indicates every feature of training set molecule is mapped, (0) indicates 1 or more features were not mapped.
In partial hit mask, (0) indicates every feature of training set molecule is mapped; (1) indicates 1 or more features were not mapped.
R: ring aromatic (RA), A: hydrogen bond acceptor (HBA), H: hydrophobic (H).