Pharmacophore Modelling and Synthesis of Quinoline-3-Carbohydrazide as Antioxidants

Table 4

DPPH radical and Superoxide radical scavenging of synthetic compounds.

Compounds	Concentration μmol·L^−1
	50 μmol·L^−1		100 μmol·L^−1		150 μmol·L^−1
% RSA*	DPPH	O2^−	DPPH	O2^−	DPPH	O2^−
8a	48±1.2	62.5±1.5	65±1.7	70±2.1	75±2	82±2.5
8b	35±1.3	38±1.1	46±1.5	45±1.2	59±1.5	58±1.7
8c	52±1.2	54.7	68±1.9	65±1.7	83±2.5	76±2.4
8d	30±1.5	24.7±1.4	55±1.7	34.5±1.5	67±1.5	45±1.8
8e	33±1.1	3.8±0.1	46±1.2	10±0.2	58±1.7	23±0.9
8f	25±0.4	21.6±0.6	35±1.1	31±1.1	50±1.2	43±1.2
8g	30±0.5	20.8±0.7	45±1.2	33±1.2	60±1.7	45±1.5
8h	13±0.3	36.5±1.1	24±0.9	46±1.4	31±1.4	55±1.6

*RSA: Radical Scavenging Activity.