Research Article

Pharmacophore Modelling and 3D-QSAR Studies on N 𝟑 -Phenylpyrazinones as Corticotropin-Releasing Factor 1 Receptor Antagonists

Figure 2

PHASE-generated pharmacophore model AADHHR.47 illustrating hydrogen bond acceptor (A2, A4; pink), hydrogen bond donor (D6; blue), hydrophobic region (H10, H11; green), and aromatic ring (R12; orange) features with distances (in Å) between different sites of AADHHR.47.
452325.fig.002