Pharmacophore Modelling and 3D-QSAR Studies on N^𝟑-Phenylpyrazinones as Corticotropin-Releasing Factor 1 Receptor Antagonists

Figure 5

3-D QSAR model based on molecule 48 of training set illustrating hydrogen bond donor feature (a), hydrogen bond acceptor feature (b) and hydrophobicity feature (c).

(a)

(b)

(c)