Research Article
Synthesis, Characterization, and Biological Evaluation of Some New Functionalized Terphenyl Derivatives
Table 1
Antibacterial activity of the synthesized compounds: MIC in μg/mL (Zone of inhibition in mm).
| | Compound | | | | | | (ATTC-25923) | (ATTC-25922) | (ATTC-27853) | (recultured) |
| | 3 | 12.5 (6) | 12.5 (6) | 12.5 (6) | 12.5 (6) | | 4 | 12.5 (6) | 12.5 (8) | 12.5 (6) | 12.5 (6) | | 5 | 12.5 (6) | 12.5 (6) | 12.5 (6) | 12.5 (8) | | 6 | 12.5 (6) | 12.5 (6) | 12.5 (6) | 12.5 (6) | | 7 | R | 100 (2) | 100 (4) | 100 (5) | | 8 | R | R | R | R | | 9a | R | R | R | R | | 9b | R | R | R | R | | 9c | R | R | R | R | | 10a | R | R | R | R | | 10b | R | R | R | R | | 10c | R | R | R | R | | 11a | R | R | R | R | | 11b | R | R | R | R | | 11c | R | R | R | R | | 12 | 100 (4) | 6.25 (6) | 6.25 (6) | 6.25 (6) | | 13 | R | R | R | R | | 14a | R | R | R | R | | 14b | R | R | R | R | | 14c | R | R | R | R | | 15a | R | R | R | R | | 15b | R | R | R | R | | 15c | R | R | R | R | | 16 | 12.5 (6) | 12.5 (6) | 12.5 (6) | 12.5 (6) | | 17a | 12.5 (6) | 12.5 (6) | 12.5 (6) | 12.5 (6) | | 17b | R | 12.5 (6) | 12.5 (6) | 12.5 (6) | | 17c | 12.5 (6) | 12.5 (6) | 12.5 (6) | 12.5 (6) | | 18 | R | R | R | R | | 19 | R | R | R | R | | Ciprofloxacin | 6.25 (20) | 6.25 (17) | 6.25 (19) | 6.25 (18) |
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Note: R indicates bacterial strains are resistant to the compounds >100 μg/mL.
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