Table 1: Relative androgenicity of androstene hormones.

HormoneEC50 (nM)AndrogenicityP value

Testosterone0.3511
Δ5-Androstene-3β, 17β-diol1.81/5<0.001
Δ5-Androstene-3β, 17α-diol211/60<0.001
Δ5-Androstene-3β, 7β, 17β-triol4641/1326<0.001

The EC50 was calculated as the 50% activation point. The androgenicity is the testosterone EC50 divided by the androstene hormone EC50. This data does not normalize the cellular uptake of androstene hormones.