Research Article

Computational Study of Estrogen Receptor-Alpha Antagonist with Three-Dimensional Quantitative Structure-Activity Relationship, Support Vector Regression, and Linear Regression Methods

Figure 4

Overlay of CoMSIA fields onto ERα binding cavity. (a) Steric, (b) electrostatic, and (c) hydrogen bond donor and (d) hydrogen bond acceptor fields. Color codes are the same as specified in Figure 3. Raloxifene is displayed in the background for reference.
743139.fig.004a
(a)
743139.fig.004b
(b)
743139.fig.004c
(c)
743139.fig.004d
(d)