Experimental Design-Based Response Surface Methodology Optimization for Synthesis of β-Mercapto Carbonyl Derivatives as Antimycobacterial Drugs Catalyzed by Calcium Pyrophosphate

Table 5

Synthesis of sulfanyl derivatives.

Products	R1	R	Yield %
3a	H	–Ph	94
3b	Cl	–Ph	96
3c	OMe	–Ph	77
3d	H	–2-NH2-Ph	93
3e	Cl	–2-NH2-Ph	95
3f	OMe	–2-NH2-Ph	92