Review Article

A Review of the Updated Pharmacophore for the Alpha 5 GABA(A) Benzodiazepine Receptor Model

Table 2

Affinity of PWZ-029 (1); (nM).

CodeMWα1α2α3α4α5α6

PWZ-029 (1)291.73>300>300>300ND38.8>300
PWZ-029 (1)291.73920NDNDND30ND
PWZ-029 (1)291.73362180328ND6ND

Data from three separate laboratories.