Research Article
Facile Synthesis, Characterization, and In Vitro Antimicrobial Screening of a New Series of 2,4,6-Trisubstituted-s-triazine Based Compounds
Table 3
The minimum inhibitory concentration (MIC)of selected 2,4,6-trisubstituted-s-triazine derivatives.
| | Compounds | MIC (μgmL−1)# | | Gram positive bacteria | Gram negative bacteria | Fungal strains | | B. subtilis | B. cereus | S. epidermidis | S. aureus | E. coli | K. pneumoniae | P. mirabilis | P. aeruginosa | C. albicans | C. tropicalis |
| | 4c | — | 100 | — | 50 | — | 12.5 | 12.5 | 25 | 6.25 | 12.5 | | 4d | 3.125 | 12.5 | 12.5 | 6.25 | — | — | — | — | — | — | | 4g | 100 | 12.5 | — | — | 6.25 | 12.5 | 12.5 | 6.25 | 3.125 | 100 | | 4h | 3.125 | 12.5 | 12.5 | 6.25 | 50 | — | — | 100 | 25 | 50 | | 4k | 50 | — | 100 | — | 6.25 | 6.25 | 25 | 12.5 | — | — | | 4n | 12.5 | 12.5 | 6.25 | 12.5 | 3.125 | 6.25 | 12.5 | 6.25 | 50 | 6.25 | | Ciprofloxacin | 3.125 | 6.25 | 6.25 | 6.25 | 3.125 | 3.125 | 6.25 | 6.25 | NT | NT | | Fluconazole | NT | NT | NT | NT | NT | NT | NT | NT | 3.125 | 6.25 |
|
|
Average of three determinations; NT: not tested; — indicates no inhibition.
|
