Benzyl-1,2,4-triazoles as CB₁ Cannabinoid Receptor Ligands: Preparation and In Vitro Pharmacological Evaluation

Scheme 2

Reagents: (i) NaOMe, dry EtOH, N₂atm; (ii) NH₄Cl, N₂atm; (iii) octanoic hydrazide, NaOMe, dry EtOH, Δ; and (iv) NaOMe, dry EtOH, Δ.