Research Article
New Conjugates of Quinoxaline as Potent Antitubercular and Antibacterial Agents
Table 3
Antibacterial and antitubercular activity of compounds synthesized (in
M).
| Comp. code | Antibacterial activity (MIC in μM) | MIC against Mycobacterium tuberculosis H37Rv (in μM) | SA | EC | PV | PA | ST |
| 1 | 29.6 | 14.8 | 29.6 | 29.6 | >59.2 | >59.2 | 2 | 13.6 | 3.6 | 13.6 | 13.6 | >54.5 | 27.2 | 3a | 14.2 | 7.1 | 14.2 | 14.2 | >28.4 | 7.1 | 3b | >28.4 | >28.4 | >28.4 | >28.4 | >28.4 | 7.1 | 3c | >19.2 | >19.2 | >19.2 | >19.2 | >19.2 | 9.6 | 3d | >19.2 | >19.2 | >19.2 | >19.2 | >19.2 | 9.6 | 3e | 2.07 | 2.07 | 2.07 | 2.07 | 7.8 | 0.65 | 3f | 2.07 | 2.07 | 3.9 | 3.9 | 15.5 | 3.9 | AMX | 0.44 | 0.87 | 1.75 | 3.28 | 1.75 | — | CIP | 1.93 | 0.96 | 3.62 | 1.93 | 7.24 | — | INH | — | — | — | — | — | 0.145 | Blank | — | — | — | — | — | — |
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