New Conjugates of Quinoxaline as Potent Antitubercular and Antibacterial Agents

Table 3

Antibacterial and antitubercular activity of compounds synthesized (in M).

Comp. code	Antibacterial activity (MIC in μM)					MIC against Mycobacterium tuberculosis H37Rv (in μM)
	SA	EC	PV	PA	ST
1	29.6	14.8	29.6	29.6	>59.2	>59.2
2	13.6	3.6	13.6	13.6	>54.5	27.2
3a	14.2	7.1	14.2	14.2	>28.4	7.1
3b	>28.4	>28.4	>28.4	>28.4	>28.4	7.1
3c	>19.2	>19.2	>19.2	>19.2	>19.2	9.6
3d	>19.2	>19.2	>19.2	>19.2	>19.2	9.6
3e	2.07	2.07	2.07	2.07	7.8	0.65
3f	2.07	2.07	3.9	3.9	15.5	3.9
AMX	0.44	0.87	1.75	3.28	1.75	—
CIP	1.93	0.96	3.62	1.93	7.24	—
INH	—	—	—	—	—	0.145
Blank	—	—	—	—	—	—