Phytochemical Study and Evaluation of the Cytotoxic Properties of Methanolic Extract from Baccharis obtusifolia

Table 2

Half maximal inhibitory concentration (IC₅₀) of the compounds isolated from Baccharis obtusifolia on cancer cell lines.

Compound	IC50  ±  SEM (μM)
	MCF-7; (breast cancer)	PC-3; (prostate cancer)	RKO; (colon cancer)	D-384; (astrocytoma)
5,4'-dihydroxy-7-methoxyflavone (1)	>100	>100	68.11 ± 1.08	>100
5-hydroxy-7,4′-dimethoxyflavone (2)	>100	>100	34.30 ± 1.34	>100

Each datum is given as the mean and its standard error (SEM) of at least three independent experiments.