Advances in Drug Design of Radiometal-Based Imaging Agents for Bone Disorders

Figure 2

Chemical structures of Tc-complex-conjugated bisphosphonate compounds (a) Tc-ECAMDP, (b) Tc-MAG3-HBP, (c) Tc-HYNIC-HBP, (d) Tc(CO)₃(κ ³-pz-BPOH)]⁺, and (e) Tc(CO)₃-DPA-alendronate.

(a)

(b)

(c)

(d)

(e)