Autoradiographic Mapping of 5-HT1B/1D Binding Sites in the Rhesus Monkey Brain Using [carbonyl-¹¹C]zolmitriptan

Table 1

The estimated 𝐵_max (receptor density) and Kd (affinity of [¹¹C]zolmitriptan) in different brain regions of the Rhesus monkey.

Brain region	𝐵max (pmol/g wet tissue)		Kd (nM)
	Mean	SE	Mean	SE
Ventral pallidum	17.9	2.6	2.2	1.1
External globus pallidus	12.2	1.4	1.3	0.6
Substantia nigra	11.4	1.6	1.0	0.6
Nucleus accumbens	9.5	0.6	1.8	0.4
Visual cortex	9.8	1.5	1.1	0.7
Frontal cortex	5.2	0.8	5.1	2.1
Cerebellum	1.6	0.4	4.9	3.4

SE: standard error.