Longitudinal Evaluation of Fatty Acid Metabolism in Normal and Spontaneously Hypertensive Rat Hearts with Dynamic MicroSPECT Imaging

Figure 6

Time-activity curves for the WKY normal rats (top two rows) and the SHRs (bottom two rows) capture quantitative differences between their spillover-corrected blood inputs and myocardial uptakes (triangles and circles, resp.). Compartmental models (solid lines) provide good fits to the myocardial uptake curves. Left column, 7 months; middle column, 14 months; right column, 21 months. SHR B died of congestive heart failure before 21 months.