A Rationale for the Use of F18-FDG PET/CT in Fever and Inflammation of Unknown Origin

Figure 1

Fifty-nine years old female male with anaemia and weight loss (CRP 56 mg/L, ESR 42 mmh/h) and vague pain in the area of the lower thoracic vertebral column. Chest radiography and US abdomen showed no abnormalities. CT of thorax and abdomen showed no abnormalities either. The F18-FDG PET/CT images showed high uptake in the gastric wall. Gastroscopy revealed gastritis with superficial ulcerae. Cultures of biopsy specimen were positive for Helicobacter pylori. After treatment with amoxicillin, clarithromycin, pantoprazole, and ferrous fumarate both CRP and ESR normalized and hemoglobin values increased to normal values. Note increased uptake bilateral in the neck due to brown adipose tissue.