Engineering Molecular Beacons for Intracellular Imaging
Figure 5
(a) Schematic of molecular beacon using L-DNA for the stem part (red) and D-DNA for the loop part (blue) [15]. (b) Principle of caged molecular beacons (cMBs) locked by covalent bonding or biotin-avidin interaction via photocleavable linkage. After light illumination, activated MBs will recover the hybridization to complementary target [27].
