Reproducible Analysis of Rat Brain PET Studies Using an Additional [¹⁸F]NaF Scan and an MR-Based ROI Template

Table 2

Volume, mean activity concentration, and total activity in various ROIs projected onto the checkerboard images with MR and PET resolution.

Brain region	MR image			PET image
	Volume; (mm^3)	Mean voxel; Activity concentration^a (kBq·mL^−1)	Mean ROI activity; (Bq)	Volume; (mm^3)	Mean voxel; Activity concentration^b (kBq·mL^−1)	Mean ROI; activity; (Bq)
Left striatum	16.4	0.50	8.19	15.3	0.52	7.95
Right striatum	15.1	0.50	7.56	14.7	0.50	7.30
Hippocampus	26.4	0.50	13.22	26.8	0.50	13.38
Frontal cortex	46.1	0.50	23.03	48.6	0.50	24.13
Posterior cortex	49.6	0.50	24.80	48.9	0.49	23.96
Medulla oblongata	15.7	0.50	7.85	15.8	0.49	7.75
Cerebellum	86.7	0.50	43.35	86.0	0.49	42.14

^a1 MR voxel =0.0013 mm³.
^b1 PET voxel =1.81 mm³.