Research Article

Synthesis of Clinical-Grade [18F]-Fluoroestradiol as a Surrogate PET Biomarker for the Evaluation of Estrogen Receptor-Targeting Therapeutic Drug

Figure 5

HPLC chromatograms for a 10 μL injection of a 0.06 μg/mL FES standard in acetonitrile. (a) is UV absorbance at 280 nm showing FES sensitivity and mobile phase impurities at this wavelength. (b) is an expanded scale of the UV absorbance at 280 nm (near the lambda max for FES). The retention time of the FES is 9.10 minutes for UV.
278607.fig.005a
(a)
278607.fig.005b
(b)