Research Article

Lyophilized Kit for the Preparation of the PET Perfusion Agent [68Ga]-MAA

Table 1

Decay corrected organ biodistribution (DC-ID/o) of 68Ga-MAA, free 68Ga, 99mTc-MAA, and hydrolyzed 99mTc.

OrganFree 68Ga 68Ga-MAA 99mTc-MAAHydrolyzed 99mTc
2 hours4 hours2 hours4 hours2 hours4 hours2 hours4 hours

Spleen0.6 ± 0.51.6 ± 0.10.1 ± 0.00.1 ± 0.00.1 ± 0.00.1 ± 0.07.2 ± 1.111.8 ± 0.7
Blood84.9 ± 4.563.1 ± 3.90.8 ± 0.80.8 ± 0.00.9 ± 0.20.9 ± 0.01.3 ± 1.20.4 ± 0.0
Rib 0.5 ± 0.41.3 ± 0.40.0 ± 0.00.0 ± 0.00.0 ± 0.00.0 ± 0.00.0 ± 0.00.0 ± 0.0
Urine6.8 ± 2.914.0 ± 1.70.1 ± 0.00.1 ± 0.07.6 ± 1.312.3 ± 1.26.1 ± 4.00.6 ± 0.2
Right kidney0.5 ± 0.51.6 ± 0.40.0 ± 0.00.0 ± 0.02.1 ± 0.13.3 ± 0.10.6 ± 0.10.4 ± 0.0
Left kidney0.5 ± 0.51.4 ± 0.20.0 ± 0.00.0 ± 0.02.2 ± 0.23.4 ± 0.20.6 ± 0.10.4 ± 0.0
Heart 0.7 ± 0.71.5 ± 0.20.0 ± 0.00.0 ± 0.00.0 ± 0.00.1 ± 0.00.2 ± 0.00.2 ± 0.0
Lungs3.1 ± 2.98.4 ± 0.398.6 ± 0.798.6 ± 0.186.6 ± 0.779.2 ± 1.539.5 ± 1.545.2 ± 10.9
Liver2.3 ± 1.97.2 ± 1.20.4 ± 0.20.4 ± 0.10.5 ± 0.00.9 ± 0.044.6 ± 2.840.9 ± 11.7