Similarities and Differences in the Glycosylation Mechanisms in Prokaryotes and Eukaryotes

Figure 2

This figure depicts key steps in the LOS and LPS biosynthetic pathway in Gram-negative bacteria which have their parallels in N- and O-glycosylation (Figures 1 and 5). For simplicity, other key steps such as the polymerization of the O-antigen prior to transfer to lipid A involved in LPS biosynthesis are not shown.