Yeast Methylotrophy: Metabolism, Gene Regulation and Peroxisome Homeostasis
Figure 3
Schematic drawing of GSH dynamics and its regulation by Yap1. The proteins enclosed within the boxes represent factors found to be induced by Yap1 at the level of transcription. Enzymes: Gsh1p: γ-glutamylcysteine synthetase; Gsh2p: glutathione synthetase; Glr1p: glutathione reducatse; Gpx: glutathione peroxidase. S-HMG: S-hydroxymethyl glutathione; GSH: reduced form of glutathione; GSSG: oxidized form of glutathione; ROS: reactive oxygen species.