Review Article

Yeast Methylotrophy: Metabolism, Gene Regulation and Peroxisome Homeostasis

Table 1

Phenotypes associated with disruptions in genes encoding methanol-metabolizing enzymes in C. boidinii.

EnzymeGene nameMutant (M)/disruptant (D) phenotypeReference

Alcohol oxidaseAOD1no growth[28]
Dihydroxyacetone synthaseDAS1no growth[29]
Formaldehyde dehydrogenaseFLD1no growth[30]
S-Formylglutathione hydrolaseFGH1weak growth[31]
Formate dehydrogenaseFDH1weak growth[32]
Alcohol dehydrogenaseADH1weak growth[33]
CatalaseCTA1weak growth[34]
Pmp20PMP20no growth[35]