Review Article
Candida albicans versus Candida dubliniensis: Why Is C. albicans More Pathogenic?
Table 1
Comparison of C. albicans and C. dubliniensis.
| | C. albicans | C. dubliniensis | References |
| Growth and morphology | | | | Growth at ≥42°C | Yes | No | [39, 41] | Growth in high salt media | Yes | No | [39, 40] | Hypha formation in YPD + serum | Yes | Poor | [16, 42] | Hypha formation in water + serum | Yes | Yes | [42] | RHE infection model | yeasts and hyphae | yeasts only | [17] |
| Genome | | | | Chromosome number | 8 | 9–11 chromosome-sized fragments | [7] | No. of species-specific genes | 168 | 29 | [32] | ALS3 | Present | Absent | [32] | HYR1 | Present | Absent | [32] | SAP4, 5 and 6 | All three genes | One gene | [32] | HWP1 | Present | Divergent | [32] | TLO family | 14 genes | 2 genes | [32] |
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