Differential Adaptations of Methicillin-Resistant Staphylococcus aureus to Serial In Vitro Passage in Daptomycin: Evolution of Daptomycin Resistance and Role of Membrane Carotenoid Content and Fluidity

Table 3

Cell membrane (CM) phospholipid composition and asymmetry of L-PG.

% of total phospholipid (mean ± SD)
Strains	Inner CM L-PG	Outer CM L-PG	Total CM L-PG	Total CM PG	Total CM CL
CB1118	11.69±0.90	1.57±0.41	13.26±0.49	84.85±1.74	1.89±1.25
CB2206	13.30±0.91	1.94±0.87	15.24±0.04	79.38±1.26	5.38±1.30
CB2207	18.94±5.00^*	2.02±0.27	20.97±4.73^*	75.33±5.55	2.90±1.96
CB2208	18.69±4.42^*	2.17±0.53	20.87±3.89^*	77.81±2.97	4.22±3.17
CB2209	13.04±2.56	2.24±0.84	15.29±1.72	83.06±1.66	1.65±0.07
CB2210	14.27±0.80	2.72±0.97	17.00±1.77^*	81.45±2.56	1.56±0.79

^*P-value < 0.05 versus parental strain.