Antifungal Resistance and New Strategies to Control Fungal Infections

Figure 2

Intracellular metabolization and action mode of 5-FC in S. cerevisiae, adapted from [11]. In bold are indicated gene names of the respective enzymes. 5-FC: 5-fluorocytosine; 5-FU: 5-fluorouracil; 5-FUMP: 5-fluorouridine monophosphate; 5-FUTP: 5-fluorouridine triphosphate; 5-FdUMP: 5-fluoro deoxyribouridine monophosphate.