In Vitro Antibacterial and Antibiotic Resistance Modifying Effect of Bioactive Plant Extracts on Methicillin-Resistant Staphylococcus epidermidis

Table 3

Interactions of plant extracts and oxacillin in effect on methicillin-resistant S. epidermidis Sep6.

Plant extract	FIC A	FIC B	FIC	Interpretation
Salvia fruticosa	0.03	0.17	0.20	Synergistic
Salvia officinalis	0.05	0.09	0.14	Synergistic
Salvia sclarea	0.06	0.09	0.15	Synergistic
Anthemis tinctoria	0.12	0.47	0.59	Additive
Chamaemelum nobile	0.13	0.41	0.54	Additive
Matricaria recutita	0.06	0.12	0.18	Synergistic
Tanacetum argyrophyllum	0.26	0.53	0.79	Additive
Tanacetum parthenicum	0.24	0.51	0.75	Additive

FIC A = MIC of substance A tested in combination/MIC of substance A tested alone, FIC B = MIC of substance B tested in combination/MIC of substance B tested alone. FIC = FIC A + FIC B. A—oxacillin, B—plant extract.